Endocrine Abstracts

A 27-year-old woman presented with severely symptomatic Graves and ophthalmopathy (FT4 49.1; TSI 53). Despite 60 mg carbimazole and 240 mg propranolol she required admission to control her symptoms and thyroid function, changing to propylthiouracil 800 mg daily with propranolol (FT4 19.9). Whilst considering thyroidectomy a 6-week pregnancy was confirmed. She relapsed (? compliance) and was admitted at 14 weeks with hyperemesis gravidarum (FT4 >77.2), which responded to an...

Historically, acute neurosurgical decompression has been considered treatment of choice for pituitary apoplexy with some studies advocating a conservative approach. We describe a patient, with reduced consciousness due to apoplexy of a gonadotroph adenoma, in whom there was spontaneous tumour shrinkage. A 68-year-old gentleman presented following a collapse with hypothermia, bradycardia and bitemporal hemianopia. Initial investigations showed low plasma sodium and glucose. Ove...